Congenital Misalignment of Pulmonary Veins with Alveolar Capillary Dysplasia Causing Persistent Neonatal Pulmonary Hypertension: Report of Two Affected Siblings

Author:

Gutierrez Carmen1,Rodriguez Angeles1,Palenzuela Sylvia1,Forteza Carolina2,Rossello Jose L. Diaz2

Affiliation:

1. Pediatric Pathology Laboratory, Hospital Pereira Rossell, Boulevard Artigas 1550, Casilla de Correo 16059, Montevideo, Uruguay

2. Latin American Center for Perinatology and Human Development, Hospital de Clínicas, Avenida Italia s/n, CP 11600, Montevideo, Uruguay

Abstract

Misalignment of pulmonary vessels with alveolar capillary dysplasia is a rare cause of persistent pulmonary hypertension of the newborn. Most of the reported cases have been sporadic. We present two consecutive affected siblings with this disorder. This is the fifth reported family occurrence of this condition. In addition to the pulmonary abnormality, one of our cases had duodenal atresia.

Publisher

SAGE Publications

Subject

General Medicine,Pathology and Forensic Medicine,Pediatrics, Perinatology, and Child Health

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