Alzheimer-like behavior and synaptic dysfunction in 3 × Tg-AD mice are reversed with calcineurin inhibition
Author:
Funder
Department of Science and Technology of Hubei Province
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s00221-024-06841-8.pdf
Reference38 articles.
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2. Amit K, Nirmal S (2017) Calcineurin inhibitors improve memory loss and neuropathological changes in mouse model of dementia. Pharmacol Biochem Behav 153:147–159. https://doi.org/10.1016/j.pbb.2016.12.018
3. Chen QS, Wei WZ, Shimahara T, Xie CW (2002) Alzheimer amyloid beta-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus. Neurobiol Learn Mem 77(3):354–371. https://doi.org/10.1006/nlme.2001.4034
4. Cummings J, Aisen P, Apostolova LG, Atri A, Setal S (2021) Aducanumab: appropriate use recommendations. The Journal of Prevention of Alzheimer’s Disease 8(4):398–410. https://doi.org/10.14283/jpad.2021.41
5. Demuro A, Mina E, Kayed R, Milton SC, Ietal P (2005) Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers. J Biol Chem 280(17):17294–17300. https://doi.org/10.1074/jbc.M500997200
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