Metformin prevents p-tau and amyloid plaque deposition and memory impairment in diabetic mice
Author:
Funder
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Publisher
Springer Science and Business Media LLC
Subject
General Neuroscience
Link
https://link.springer.com/content/pdf/10.1007/s00221-021-06176-8.pdf
Reference84 articles.
1. Advani A, Connelly KA, Advani SL et al (2013) Role of the eNOS-NO system in regulating the antiproteinuric effects of VEGF receptor 2 inhibition in diabetes. Biomed Res Int 2013:201475. https://doi.org/10.1155/2013/201475
2. Alberdi E, Sánchez-Gómez MV, Cavaliere F et al (2010) Amyloid β oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors. Cell Calcium 47:264–272. https://doi.org/10.1016/j.ceca.2009.12.010
3. Allard JS, Perez EJ, Fukui K et al (2016) Prolonged metformin treatment leads to reduced transcription of Nrf2 and neurotrophic factors without cognitive impairment in older C57BL/6J mice. Behav Brain Res 301:1–9. https://doi.org/10.1016/j.bbr.2015.12.012
4. Alvarez EO, Beauquis J, Revsin Y et al (2009) Cognitive dysfunction and hippocampal changes in experimental type 1 diabetes. Behav Brain Res 198:224–230. https://doi.org/10.1016/j.bbr.2008.11.001
5. Arrick DM, Sharpe GM, Sun H, Mayhan WG (2007) Diabetes-induced cerebrovascular dysfunction: role of poly(ADP-ribose) polymerase. Microvasc Res 73:1–6. https://doi.org/10.1016/j.mvr.2006.08.001
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