5-HT2A blockade for dyskinesia and psychosis in Parkinson’s disease: is there a limit to the efficacy of this approach? A study in the MPTP-lesioned marmoset and a literature mini-review-Reference-Cited by-同舟云学术

5-HT2A blockade for dyskinesia and psychosis in Parkinson’s disease: is there a limit to the efficacy of this approach? A study in the MPTP-lesioned marmoset and a literature mini-review

Published:2018-11-15 Issue:2 Volume:237 Page:435-442
ISSN:0014-4819
Container-title:Experimental Brain Research
language:en
Short-container-title:Exp Brain Res

Author:

Kwan Cynthia,Frouni Imane,Bédard Dominique,Nuara Stephen G.,Gourdon Jim C.,Hamadjida Adjia,Huot Philippe

Funder

Weston Brain Institute

Publisher

Springer Science and Business Media LLC

Subject

General Neuroscience

Link

http://link.springer.com/article/10.1007/s00221-018-5434-9/fulltext.html

Reference33 articles.

1. Bartoszyk GD, van Amsterdam C, Bottcher H, Seyfried CA (2003) EMD 281014, a new selective serotonin 5-HT2A receptor antagonist. Eur J Pharmacol 473:229–230

2. Bhattacharyya S, Raote I, Bhattacharya A, Miledi R, Panicker MM (2006) Activation, internalization, and recycling of the serotonin 2A receptor by dopamine. Proc Natl Acad Sci USA 103:15248–15253. https://doi.org/10.1073/pnas.0606578103

3. Connolly BS, Lang AE (2014) Pharmacological treatment of Parkinson disease: a review. JAMA 311:1670–1683

4. Cummings J, Isaacson S, Mills R et al (2014) Pimavanserin for patients with Parkinson’s disease psychosis: a randomised, placebo-controlled phase 3 trial. Lancet 383:533–540. https://doi.org/10.1016/S0140-6736(13)62106-6

5. Durif F, Debilly B, Galitzky M et al (2004) Clozapine improves dyskinesias in Parkinson disease: a double-blind, placebo-controlled study. Neurology 62:381–388

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