Weekly 5-fluorouracil and folinic acid plus escalating doses of cisplatin with gluthatione protection in patients with advanced head and neck cancer

Author:

Gebbia Vittorio,Valenza Roberto,Testa Antonio,Zerillo Giuseppe,Restivo Salvatore,Cupido Gianfranco,Ingria Federico,Spadafora Giovanni,Barbaccia Carmelo,Cannata Giuseppe,Cipolla Calogero,Gebbia Nicola

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference24 articles.

1. Al Sarraf M: Head and neck cancer: chemotherapy concepts.Sern Oncol 15, 70 (1988).

2. Scanlon K J, Newman E M, Lu Y, Priest D G: Biochemical basis for cisplatin and 5fluorouracil synergism in human ovarian carcinoma cells.Proc Natl Acad Sci USA 83, 8923 (1986).

3. Schabel F M. Trader M W, Laster W R, Corbett T H. Griswold DP: Cisdichlorodiamminoplatinum: combination chemotherapy and cross resistance studies with tumor of mice.Cancer Treat Rep 83, 1459 (1979).

4. Palmen S, Gebbia V, Russo A, Gebbia N, Oliven D, Rausa L: Cis-diamminodichloroplatinum plus 5-day continuous infusion of 5-Fluorouracil in the treatment of recurrent and metastatic head and neck cancer patients.J Cancer Res Clin Oncol 5, 579–582 (1989).

5. Santi D V, McHenry C S, Sommer H: Mechanisms of interaction of thymidilate synthetase with 5-fluorode-oxyuridylate.Biochemistry 13, 471 (1974).

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