Synthesis and active manipulation of magnetic liquid beads

Author:

Yadav Ajeet Singh,Galogahi Fariba Malekpour,Vashi Aditya,Tran Du Tuan,Kijanka Gregor S.,Cha Haotian,Sreejith Kamalalayam Rajan,Nguyen Nam-Trung

Abstract

AbstractWe report the fabrication and characterisation of magnetic liquid beads with a solid magnetic shell and liquid core using microfluidic techniques. The liquid beads consist of a fluorinated oil core and a polymer shell with magnetite particles. The beads are generated in a flow-focusing polydimethylsiloxane (PDMS) device and cured by photo polymerisation. We investigated the response of the liquid beads to an external magnetic field by characterising their motion towards a permanent magnet. Magnetic sorting of liquid beads in a channel was achieved with 90% efficiency. The results show that the liquid beads can be controlled magnetically and have potential applications in digital microfluidics including nucleic acid amplification, drug delivery, cell culture, sensing, and tissue engineering. The present paper also discusses the magnetophoretic behaviour of the liquid bead by varying its mass and magnetite concentration in the shell. We also demonstrated the two-dimensional self-assembly of magnetic liquid beads for potential use in digital polymerase chain reaction and digital loop mediated isothermal amplification. Graphical abstract

Funder

Australian Research Council

Griffith University

Publisher

Springer Science and Business Media LLC

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Micro container made of levitated liquid bead;Colloids and Surfaces A: Physicochemical and Engineering Aspects;2024-12

2. Micro Container Made of Levitated Liquid Bead;2024

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