Abstract
AbstractRNA interference (RNAi) is being developed and exploited to improve plants by modifying endogenous gene expression as well as to target pest and pathogen genes both within plants (i.e. host-induced gene silencing) and/or as topical applications (e.g. spray-induced gene silencing). RNAi is a natural mechanism which can be exploited to make a major contribution towards integrated pest management and sustainable agricultural strategies needed worldwide to secure current and future food production. RNAi plants are being assessed and regulated using existing regulatory frameworks for GMO. However, there is an urgent need to develop appropriate science-based risk assessment procedures for topical RNAi applications within existing plant protection products legislation.
Funder
European Cooperation in Science and Technology
Publisher
Springer Science and Business Media LLC
Subject
Agronomy and Crop Science
Reference33 articles.
1. Andrade EC, Hunter WB (2016) RNA interference – natural gene-based technology for highly specific pest control (HiSPeC). In: Abdurakhmonov IY (ed) RNA interference. InTech, Rijeka, pp 391–409
2. Bachman PM, Bolognesi R, Moar WJ et al (2013) Characterization of the spectrum of insecticidal activity of a double-stranded RNA with targeted activity against Western Corn Rootworm (Diabrotica virgifera virgifera LeConte). Transgenic Res 22:1207–1222
3. Baum JA, Bogaert T, Clinton W et al (2007) Control of coleopteran insect pests through RNA interference. Nat Biotechnol 25:1322–1326
4. Cagliari D, Dias N, Avila Dos Santos E, Galdeano DM, Smagghe G, Zotti MJ (2019) Management of pest insects and plant diseases by non-transformative RNAi. Frontiers Plant Sci 10:1319
5. Casacuberta JM, Devos Y, Du Jardin P et al (2015) Biotechnological uses of RNAi in plants: risk assessment considerations. Trends Biotechnol 33:145–147
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