On the Roles of Calcineurin in Fungal Growth and Pathogenesis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases
Link
http://link.springer.com/content/pdf/10.1007/s12281-010-0027-5.pdf
Reference93 articles.
1. Klee CB, Crouch TH, Krinks MH: Calcineurin: a calcium- and calmodulin-binding protein of the nervous system. Proc Natl Acad Sci USA 1979, 76:6270–6273.
2. •• Steinbach WJ, Reedy JL, Cramer RA Jr, et al.: Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections. Nat Rev Microbiol 2007, 5:418–430. This article reviews the roles of calcineurin pathways in the growth and virulence of three major human fungal pathogens, C. albicans, C. neoformans, and A. fumigatus.
3. Crabtree GR, Schreiber SL: SnapShot: Ca2+-calcineurin-NFAT signaling. Cell 2009, 138:210.
4. • Baek KH, Zaslavsky A, Lynch RC, et al.: Down’s syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature 2009, 459:1126–1130. This article reports the discovery that an increased level of a CNI, Dscr1 (Down syndrome candidate region-1), in Down syndrome tissues markedly diminishes angiogenesis and constrains tumor formation.
5. Aramburu J, Heitman J, Crabtree GR: Calcineurin: a central controller of signalling in eukaryotes. EMBO Rep 2004, 5:343–348.
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