MST1: a promising therapeutic target to restore functional beta cell mass in diabetes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00125-016-3892-9.pdf
Reference48 articles.
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2. Herold KC, Usmani-Brown S, Ghazi T et al (2015) Beta cell death and dysfunction during type 1 diabetes development in at-risk individuals. J Clin Invest 125:1163–1173
3. Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC (2003) Beta cell deficit and increased beta cell apoptosis in humans with type 2 diabetes. Diabetes 52:102–110
4. Mathis D, Vence L, Benoist C (2001) Beta cell death during progression to diabetes. Nature 414:792–798
5. Ardestani A, Paroni F, Azizi Z et al (2014) MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes. Nat Med 20:385–397
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