An unclear role for the GLP-1 metabolite GLP-1(9–36) in human islet physiology
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Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s00125-024-06141-4.pdf
Reference9 articles.
1. Gandasi NR, Gao R, Kothegala L et al (2024) GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion. Diabetologia 67:528–546. https://doi.org/10.1007/s00125-023-06060-w
2. Hansen L, Deacon CF, Orskov C, Holst JJ (1999) Glucagon-like peptide-1-(7–36)amide is transformed to glucagon-like peptide-1-(9–36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine. Endocrinology 140:5356–5363. https://doi.org/10.1210/endo.140.11.7143
3. Vahl TP, Paty BW, Fuller BD, Prigeon RL, D’Alessio DA (2003) Effects of GLP-1-(7–36)NH2, GLP-1-(7–37), and GLP-1-(9–36)NH2 on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans. J Clin Endocrinol Metab 88:1772–1779. https://doi.org/10.1210/jc.2002-021479
4. Elahi D, Egan JM, Shannon RP et al (2008) GLP-1 (9–36) amide, cleavage product of GLP-1 (7–36) amide, is a glucoregulatory peptide. Obesity (Silver Spring) 16:1501–1509. https://doi.org/10.1038/oby.2008.229
5. Sathananthan M, Farrugia LP, Miles JM et al (2013) Direct effects of exendin-(9,39) and GLP-1-(9,36)amide on insulin action, beta-cell function, and glucose metabolism in nondiabetic subjects. Diabetes 62:2752–2756. https://doi.org/10.2337/db13-0140
Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Molecular basis of enhanced GLP-1 signaling mediated by GLP-1(9-36) in conjunction with LSN3318839;Acta Pharmaceutica Sinica B;2024-09
2. Molecular basis of enhanced GLP-1 signaling mediated by GLP-1(9-36) in conjunction with LSN3318839;2024-07-22
3. An unclear role for the GLP-1 metabolite GLP-1(9–36) in human islet physiology. Reply to Matveyenko A, Vella A [letter];Diabetologia;2024-04-05
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