Bioelectronic modulation of carotid sinus nerve activity in the rat: a potential therapeutic approach for type 2 diabetes

Author:

Sacramento Joana F.,Chew Daniel J.,Melo Bernardete F.,Donegá Matteo,Dopson Wesley,Guarino Maria P.,Robinson Alison,Prieto-Lloret Jesus,Patel Sonal,Holinski Bradley J.,Ramnarain Nishan,Pikov Victor,Famm Kristoffer,Conde Silvia V.

Funder

Fundação para a Ciência e a Tecnologia

Galvani Bioelectronics

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference35 articles.

1. EMA (2012) Guideline on clinical investigation of medicinal products in the treatment or prevention of diabetes mellitus. Available from: www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2012/06/WC500129256.pdf . Accessed 20 June 2017

2. IDF (2015) IDF diabetes atlas (7th edition). Available from: www.diabetesatlas.org/ . Accessed 20 June 2017

3. World Health Organization (2016) Diabetes fact sheet. Available from: www.who.int/mediacentre/factsheets/fs312/en/ . Accessed 20 June 2017

4. Ribeiro MJ, Sacramento JF, Gonzalez C et al (2013) Carotid body denervation prevents the development of insulin resistance and hypertension induced by hypercaloric diets. Diabetes 62:2905–2916

5. Sacramento JF, Ribeiro MJ, Rodrigues T et al (2017) Functional abolishment of carotid body activity restores insulin action and glucose homeostasis: key roles for visceral adipose tissue and the liver. Diabetologia 60:158–168

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