Endosomal proteolysis of internalised [ArgA0]-human insulin at neutral pH generates the mature insulin peptide in rat liver in vivo
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00125-009-1551-0.pdf
Reference37 articles.
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4. Brennan SO, Peach RJ (1991) The processing of human proinsulin and chicken proalbumin by rat hepatic vesicles suggests a convertase specific for X–Y–Arg–Arg or Arg–X–Y–Arg sequences. J Biol Chem 266:21504–21508
5. Vollenweider F, Irminger JC, Gross DJ, Villa-Komaroff L, Halban PA (1992) Processing of proinsulin by transfected hepatoma (FAO) cells. J Biol Chem 267:14629–14636
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