DEXI, a candidate gene for type 1 diabetes, modulates rat and human pancreatic beta cell inflammation via regulation of the type I IFN/STAT signalling pathway-Reference-Cited by-同舟云学术

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DEXI, a candidate gene for type 1 diabetes, modulates rat and human pancreatic beta cell inflammation via regulation of the type I IFN/STAT signalling pathway

Published:2018-11-26 Issue:3 Volume:62 Page:459-472
ISSN:0012-186X
Container-title:Diabetologia
language:en
Short-container-title:Diabetologia

Author:

Dos Santos Reinaldo S.,Marroqui Laura,Velayos Teresa,Olazagoitia-Garmendia Ane,Jauregi-Miguel Amaia,Castellanos-Rubio Ainara,Eizirik Decio L.,Castaño Luis,Santin Izortze^ORCID

Funder

Horizon 2020 Program T2D systems

NIH-NIDDK-HIRN Consortium

INNODIA

Basque Department of Health

Fundación de la Sociedad Española de Diabetes

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://link.springer.com/article/10.1007/s00125-018-4782-0/fulltext.html

Reference45 articles.

1. Eizirik DL, Colli ML, Ortis F (2009) The role of inflammation in insulitis and beta-cell loss in type 1 diabetes. Nat Rev Endocrinol 5(4):219–226. https://doi.org/10.1038/nrendo.2009.21

2. Santin I, Eizirik DL (2013) Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and beta-cell apoptosis. Diabetes Obes Metab 15(s3):71–81. https://doi.org/10.1111/dom.12162

3. Dotta F, Censini S, Van Halteren AGS et al (2007) Coxsackie B4 virus infection of β cells and natural killer cell insulitis in recent-onset type 1 diabetic patients. Proc Natl Acad Sci U S A 104(12):5115–5120. https://doi.org/10.1073/pnas.0700442104

4. Yeung W-CG, Rawlinson WD, Craig ME (2011) Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies. BMJ 342:d35–d35. https://doi.org/10.1136/bmj.d35

5. Marroqui L, Lopes M, dos Santos RS et al (2015) Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells. Elife 4:1–23

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