IKKβ inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents-Reference-Cited by-同舟云学术

IKKβ inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents

Published:2017-07-20 Issue:10 Volume:60 Page:2021-2032
ISSN:0012-186X
Container-title:Diabetologia
language:en
Short-container-title:Diabetologia

Author:

Ivovic Aleksandar,Oprescu Andrei I.,Koulajian Khajag,Mori Yusaku,Eversley Judith A.,Zhang Liling,Nino-Fong Rodolfo,Lewis Gary F.,Donath Marc Y.,Karin Michael,Wheeler Michael B.,Ehses Jan,Volchuk Allen,Chan Catherine B.,Giacca Adria

Funder

Showa University

Canadian Institutes of Health Research

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://link.springer.com/article/10.1007/s00125-017-4345-9/fulltext.html

Reference50 articles.

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2. Oprescu AI, Bikopoulos G, Naassan A et al (2007) Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo. Diabetes 56:2927–2937

3. Xiao C, Giacca A, Lewis GF (2008) Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, non-diabetic men. Diabetologia 51:139–146

4. Norlin S, Ahlgren U, Edlund H (2005) Nuclear factor-κB activity in β-cells is required for glucose-stimulated insulin secretion. Diabetes 54:125–132

5. Giannoukakis N, Rudert WA, Trucco M, Robbins PD (2000) Protection of human islets from the effects of interleukin-1 by adenoviral gene transfer of an Iκ Bα repressor. J Biol Chem 275:36509–36513

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