SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes

Author:

van Diepen Janna A.,Robben Joris H.,Hooiveld Guido J.,Carmone Claudia,Alsady Mohammad,Boutens Lily,Bekkenkamp-Grovenstein Melissa,Hijmans Anneke,Engelke Udo F. H.,Wevers Ron A.,Netea Mihai G.,Tack Cees J.,Stienstra Rinke,Deen Peter M. T.

Funder

Nierstichting

European Foundation for the Study of Diabetes

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference28 articles.

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3. Gao D, Madi M, Ding C et al (2014) Interleukin-1beta mediates macrophage-induced impairment of insulin signaling in human primary adipocytes. Am J Phys Endocrinol Metab 307:E289–E304

4. Tannahill GM, Curtis AM, Adamik J et al (2013) Succinate is an inflammatory signal that induces IL-1beta through HIF-1alpha. Nature 496:238–242

5. Toma I, Kang JJ, Sipos A et al (2008) Succinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidney. J Clin Invest 118:2526–2534

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