The risk of progression to type 1 diabetes is highly variable in individuals with multiple autoantibodies following screening
Author:
Funder
TrialNet is supported by NIH and JDRF
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00125-019-05047-w.pdf
Reference36 articles.
1. Ziegler AG, Hummel M, Schenker M, Bonifacio E (1999) Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study. Diabetes. 48(3):460–468. https://doi.org/10.2337/diabetes.48.3.460
2. Steck AK, Vehik K, Bonifacio E et al (2015) Predictors of progression from the appearance of islet autoantibodies to early childhood diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY). Diabetes Care 38(5):808–813. https://doi.org/10.2337/dc14-2426
3. Vehik K, Lynch KF, Schatz DA et al (2016) Reversion of β-cell autoimmunity changes risk of type 1 diabetes: TEDDY Study. Diabetes Care 39(9):1535–1542. https://doi.org/10.2337/dc16-0181
4. ClinicalTrials.gov (2017) Type 1 Diabetes Prediction and Prevention (DIPP) Study (DIPP). Available from https://clinicaltrials.gov/ct2/show/NCT03269084. Accessed 2 February 2018
5. Ziegler AG, Rewers M, Simell O et al (2013) Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA 309(23):2473–2479. https://doi.org/10.1001/jama.2013.6285
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