A fluorescence-based high throughput assay for the determination of small molecule−human serum albumin protein binding
Author:
Publisher
Springer Science and Business Media LLC
Subject
Biochemistry,Analytical Chemistry
Link
http://link.springer.com/content/pdf/10.1007/s00216-013-7560-3.pdf
Reference29 articles.
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3. Lázaro E, Lowe PJ, Briand X, Faller B (2008) New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin. J Med Chem 51(7):2009–2017
4. Ballard P, Rowland M (2011) Correction for nonspecific binding to various components of ultrafiltration apparatus and impact on estimating in vivo rat clearance for a congeneric series of 5-ethyl, 5-n-alkyl barbituric acids. Drug Metab Dispos 39(12):2165–2168
5. Valko K, Nunhuck S, Bevan C, Abraham MH, Reynolds DP (2003) Fast gradient HPLC method to determine compounds binding to human serum albumin. Relationships with octanol/water and immobilized artificial membrane lipophilicity. J Pharm Sci 92:2236–2248
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