Pharmacodynamic assay of thymidylate synthase activity in peripheral blood mononuclear cells-Reference-Cited by-同舟云学术

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Pharmacodynamic assay of thymidylate synthase activity in peripheral blood mononuclear cells

Published:2013-01-12 Issue:8 Volume:405 Page:2495-2503
ISSN:1618-2642
Container-title:Analytical and Bioanalytical Chemistry
language:en
Short-container-title:Anal Bioanal Chem

Author:

Pluim Dick,Schilders Kim A. A.,Jacobs Bart A. W.,Vaartjes Daniëlle,Beijnen Jos H.,Schellens Jan H. M.

Publisher

Springer Science and Business Media LLC

Subject

Biochemistry,Analytical Chemistry

Link

http://link.springer.com/content/pdf/10.1007/s00216-012-6676-1.pdf

Reference25 articles.

1. Takezawa K, Okamoto I, Tsukioka S, Uchida J, Kiniwa M, Fukuoka M, Nakagawa K (2010) Identification of thymidylate synthase as a potential therapeutic target for lung cancer. Br J Cancer 103:354–361

2. Costi MP, Ferrari S, Venturelli A, Calo S, Tondi D, Barlocco D (2005) Thymidylate synthase structure, function and implication in drug discovery. Curr Med Chem 12:2241–2258

3. Derenzini M, Montanaro L, Trere D, Chilla A, Tazzari PL, Dall’Olio F, Ofner D (2002) Thymidylate synthase protein expression and activity are related to the cell proliferation rate in human cancer cell lines 3. Mol Pathol 55:310–314

4. Bertino JR, Silber R, Freeman M, Alenty A, Albrecht M, Gabrio BW, Huennekens FM (1963) Studies on normal and leukemic leukocytes. IV. Tetrahydrofolate-dependent enzyme systems and dihydrofolic reductase 1. J Clin Invest 42:1899–1907

5. Rao KN, Bhattacharya RK, Venkatachalam SR (1998) Thymidylate synthase activity and the cell growth are inhibited by the beta-carboline-benzoquinolizidine alkaloid deoxytubulosine. J Biochem Mol Toxicol 12:167–173

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1. Phase I pharmacological study of continuous chronomodulated capecitabine treatment;Pharmaceutical Research;2020-05

2. Thymidylate synthase maintains the de-differentiated state of triple negative breast cancers;Cell Death & Differentiation;2019-02-08

3. Development and validation of a quantitative method for thymidine phosphorylase activity in peripheral blood mononuclear cells;Nucleosides, Nucleotides and Nucleic Acids;2018-08-03

4. Thymidylate synthase maintains the de-differentiated state of aggressive breast cancers;2018-05-14

5. Dihydrofolate Reductase/Thymidylate Synthase Fine-Tunes the Folate Status and Controls Redox Homeostasis in Plants;The Plant Cell;2017-09-22

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