A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study

Author:

Parker Suzanne L.,Pandey Saurabh,Sime Fekade B.,Lipman Jeffrey,Roberts Jason A.,Wallis Steven C.

Funder

Melinta Therapeutics, USA

Publisher

Springer Science and Business Media LLC

Subject

Biochemistry,Analytical Chemistry

Reference38 articles.

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2. U.S. Food and Drug Administration. FDA approves new antibacterial drug. 2017.

3. Eurpean Medicines Agency (EMA). Zerbaxa: EPAR - Product Information. 2018.

4. Sakoulas G. Meropenem/vaborbactam approved in U.S. for Complicated Urinary Tract Infection. NEJM Group; 2018. https://www.jwatch.org/na45133/2017/10/18/meropenem-vaborbactam-approved-us-complicated-urinary. Accessed 12 Sept 2019.

5. Alexander EL, Loutit J, Tumbarello M, Wunderink R, Felton T, Daikos G, et al. Carbapenem-resistant Enterobacteriaceae infections: results from a retrospective series and implications for the design of prospective clinical trials. Open Forum Infect Dis. 2017;4(2). https://doi.org/10.1093/ofid/ofx063.

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