Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters

Author:

Breveglieri Giulia,Salvatori Francesca,Finotti Alessia,Cosenza Lucia Carmela,Zuccato Cristina,Bianchi Nicoletta,Breda Laura,Rivella Stefano,Bresciani Alberto,Bisbocci Monica,Borgatti Monica,Gambari Roberto

Publisher

Springer Science and Business Media LLC

Subject

Biochemistry,Analytical Chemistry

Reference41 articles.

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2. Gambari R. Foetal hemoglobin inducers and thalassemia: novel achievements. Blood Transfus. 2009;8:5–7.

3. Ataga KI. Novel therapies in sickle cell disease. Hematology. 2009;2009:54–61.

4. Fard AD, Hosseini SA, Shahjahani M, Salari F, Jaseb K. Evaluation of novel fetal hemoglobin inducer drugs in treatment of β-hemoglobinopathy disorders. Int J Hematol Oncol Stem Cell Res. 2013;7:47–54.

5. Fibach E, Burke LP, Schechter AN, Noguchi CT, Rodgers GP. Hydroxyurea increases fetal hemoglobin in cultured erythroid cells derived from normal individuals and patients with cell anemia or β-thalassemia. Blood. 1993;81:1630–5.

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