Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors
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Published:2022-06-13
Issue:5
Volume:380
Page:
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ISSN:2365-0869
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Container-title:Topics in Current Chemistry
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language:en
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Short-container-title:Top Curr Chem (Z)
Author:
Wu Miaomiao, Zhang Zexi, Yong Jiaxi, Schenk Peer M., Tian Dihua, Xu Zhi Ping, Zhang RunORCID
Abstract
AbstractLuminescence chemosensors are one of the most useful tools for the determination and imaging of small biomolecules and ions in situ in real time. Based on the unique photo-physical/-chemical properties of ruthenium(II) (Ru(II)) complexes, the development of Ru(II) complex-based chemosensors has attracted increasing attention in recent years, and thus many Ru(II) complexes have been designed and synthesized for the detection of ions and small biomolecules in biological and environmental samples. In this work, we summarize the research advances in the development of Ru(II) complex-based chemosensors for the determination of ions and small biomolecules, including anions, metal ions, reactive biomolecules and amino acids, with a particular focus on binding/reaction-based chemosensors for the investigation of intracellular analytes’ evolution through luminescence analysis and imaging. The advances, challenges and future research directions in the development of Ru(II) complex-based chemosensors are also discussed.
Funder
Australian Research Council National Health and Medical Research Council The University of Queensland
Publisher
Springer Science and Business Media LLC
Subject
General Chemistry
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