The tetracycline analogs minocycline and doxycycline inhibit angiogenesis in vitro by a non-metalloproteinase-dependent mechanism

Author:

Gilbertson-Beadling S.,Powers E. A.,Stamp-Cole M.,Scott P. S.,Wallace T. L.,Copeland J.,Petzold G.,Mitchell M.,Ledbetter S.,Poorman R.,Wilks J. W.,Fisher C.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference33 articles.

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2. Burns FR, Stack MS, Gray RD, Paterson CA (1989) Inhibition of purified collagenase from alkali-burned rabbit corneas. Invest Ophthalmol Vis Sci 30(7): 1569?1575

3. Campion C, Davidson AH, Dickens JP, Crimmin MJ (1990) Hydroxamic acid based collagenase inhibitors. British Biotechnology Patent WO 90/05719

4. Cawston, TE, Barrett AJ (1979) A rapid and reproducible assay for collagenase using [1-14C]acetylated collagen. Anal Biochem 99: 340?345

5. Davies B, Brown PD, East N, Crimmen MJ, Balkwill FR (1993) A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts. Cancer Res 53: 2787?2791

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