High-performance liquid chromatography (HPLC): A rapid, flexible and sensitive method for separating islet proinsulin and insulin
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://link.springer.com/content/pdf/10.1007/BF00870146.pdf
Reference9 articles.
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2. Halban PA (1982) Inhibition of proinsulin to insulin conversion in rat islets using arginine and lysine analogs: lack of effect on rate of release of modified products. J Biol Chem 257: 13177?13180
3. Clark JL, Steiner DF (1969) Insulin biosynthesis in the rat: demonstration of two proinsulins. Proc Natl Acad Sci USA 62: 278?285
4. Kakita K, O'Connell K, Permutt MA (1982) Pancreatic content of insulins I and II in laboratory rodents: analysis by immunoelectrophoresis. Diabetes 31: 841?845
5. Shoelson S, Hareda M, Blix P, Nanjo A, Sanke T, Inouye K, Steiner D, Rubenstein A, Tager H (1983) Three mutant insulins in man. Nature 302: 540?543
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