A peptide derived from TIMP-3 inhibits multiple angiogenic growth factor receptors and tumour growth and inflammatory arthritis in mice

Author:

Chen Yung-Yi,Brown Nicola J.,Jones Rita,Lewis Claire E.,Mujamammi Ahmed H.,Muthana Munitta,Seed Michael P.,Barker Michael D.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Clinical Biochemistry,Physiology

Reference45 articles.

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3. Fassina G, Ferrari N, Brigati C, Benelli R, Santi L, Noonan DM, Albini A (2000) Tissue inhibitors of metalloproteases: regulation and biological activities. Clin Exp Metastasis 18(2):111–120

4. Qi JH, Ebrahem Q, Moore N, Murphy G, Claesson-Welsh L, Bond M, Baker A, Anand-Apte B (2003) A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat Med 9(4):407–415

5. Langton KP, McKie N, Curtis A, Goodship JA, Bond PM, Barker MD, Clarke M (2000) A novel tissue inhibitor of metalloproteinases-3 mutation reveals a common molecular phenotype in Sorsby’s fundus dystrophy. J Biol Chem 275(35):27027–27031

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