Plasma levels of angiopoietin-2, VEGF-A, and VCAM-1 as markers of bevacizumab-induced hypertension: CALGB 80303 and 90401 (Alliance)

Author:

Quintanilha Julia C. F.,Liu Yingmiao,Etheridge Amy S.,Yazdani Akram,Kindler Hedy L.,Kelly William Kevin,Nixon Andrew B.,Innocenti Federico

Funder

National Cancer Institute of the National Institutes of Health

Foundation for the National Institutes of Health

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Clinical Biochemistry,Physiology

Reference48 articles.

1. Garcia J, Hurwitz HI, Sandler AB et al (2020) Bevacizumab (Avastin®) in cancer treatment: a review of 15 years of clinical experience and future outlook. Cancer Treat Rev 86:102017

2. EMA summary of product characteristics (2017). https://www.ema.europa.eu/en/documents/product-information/avastin-epar-product-information_en.pdf. Accessed 05 Oct 2020

3. FDA AVASTIN®prescribing information (2020). https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/125085s332lbl.pdf. Accessed 05 Oct 2020

4. Quintanilha JCF, Wang J, Sibley AB et al (2020) Bevacizumab-induced hypertension and proteinuria: a genome-wide analysis of more than 1,000 patients. Eur J Cancer 138:S9–S10

5. Moslehi JJ (2016) Cardiovascular toxic effects of targeted cancer therapies. N Engl J Med 375:1457–1467

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