Prevention of Colorectal Cancer by Aspirin and/or Calcium: Efficacy, Mechanisms, and Cost Effectiveness
Author:
Publisher
Springer Science and Business Media LLC
Subject
Gastroenterology,Oncology,Hepatology
Link
http://link.springer.com/content/pdf/10.1007/s11888-011-0115-0.pdf
Reference22 articles.
1. Pence BC, Buddingh F. Inhibition of dietary fat-promoted colon carcinogenesis in rats by supplemental calcium or vitamin D3. Carcinogenesis. 1988;9:1887–90. This is the first article reporting that dietary calcium can prevent colon cancer in a preclinical study.
2. Carroll C, Cooper K, Papioannou D, et al. Supplemental calcium in the chemoprevention of colorectal cancer: a systematic review and meta-analysis. Clin Ther. 2010;32:789–803.
3. Baron JA, Cole BF, Sandler RS, et al. A randomized trial of aspirin to prevent colorectal adenomas. N Engl J Med. 2003;348:891–9. This randomized controlled trial showed that aspirin (81 mg/day) had a moderate chemopreventive effect on adenomas in the colon.
4. Dube C, Rostom A, Lewin G, et al. The use of aspirin for primary prevention of colorectal cancer: a systematic review prepared for the U.S. Preventive Services Task Force. Ann Intern Med. 2007;146:365–75.
5. Rothwell PM, Wilson M, Elwin C-E, et al. Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomized trials. Lancet. 2010;376:1741–50. Aspirin taken for 5 years or longer at a dose of 75 mg/day reduced long-term incidence and mortality for CRC.
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1. Combination Aspirin and/or Calcium Chemoprevention with Colonoscopy in Colorectal Cancer Prevention: Cost-effectiveness Analyses;Cancer Epidemiology Biomarkers & Prevention;2012-12-18
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