Comparison of the disposition and of the metabolic pattern of Reboxetine, a new antidepressant, in the rat, dog, monkey and man

Author:

Cocchiara G.,Battaglia R.,Pevarello P.,Benedetti M. Strolin

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference6 articles.

1. Melloni P., Carniel G., Delia Torre A., et al. (1984): Potential antidepressant agents. a-Aryloxy-benzyl derivatives of ethanolamine and morpholine. Eur. J. Med. Chem., 19, 235–242.

2. Ban T.A., Vergara L., Albrecht J., {eaet al.} (1987): Reboxetine: a potential new antidepressant - report on a therapeutic dose range finding study. International Conference on New Directions in Affective Disorders, Jerusalem, 5-9 April, Abstract p73.

3. Cocchiara G., Melloni P., Battaglia R., Vicario G.P., Strolin Benedetti M. (1988): Urinary metabolism of 1 4C-labelled Reboxetine in various animal species. In: Proceedings of Eleventh European Workshop on Drug Metabolism, edited by European Society of Biochemical Pharmacology, Abstract no. 3 32.

4. Drenth B.F.H., Jagersma T., Overzet F., Ghijsen R.T., Zeeuw R.A. (1983): Assessment of radioactivity measurements on HPLC effluents. In: Reid E., Leppard J.P. eds. Drug Metabolite Isolation and Determination, Vol 12. New York, Plenum Press, pp. 75–80

5. Case D.E., Illston H., Reeves P.R., Shuker B., Simons P. (1975): The disposition and metabolism of I.C.I. 58,834 (Viloxazine) in animals. Xenobiotica, 5, 83–111.

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