N-Dephenylated and N-phenyl urinary metabolites of mociprazine (CERM 3517) in beagle dogs after oral administration. A mass spectrometric determination

Author:

Enreille A.,Pognat J. F.,Galmter M. J.,Larttgue-Mattei C.,Chabard J. L.,Busch N.,Berger J. A.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference13 articles.

1. CERM (1975): US Patent 3, May 20, 884, 923.

2. Pognat J.F., Enreille A., Chabard JL., Busch N., Berger J.A. (1986): N-dephenylation of CERM 3517 (mociprazine) in Beagle dogs, a mass spectrometric determination. Drug Metab. Dispos., 14,147–154.

3. Batten P.L., Hathway D.E. (1977): Dephenylation of N-phenyl-2-naphthylamine in dogs and its possible oncogenic implications. Br. J. Cancer, 22, 342.

4. Anderson M.M., Mitchum R.H., Beland F.A. (1982): Hepatic microsomal metabolism and macromolecular binding of the antioxydant, N-phenyl-2-naphthylamine. Xenobiotica, 12, 31–43.

5. Heykants J., Pardoel L., Janssen P.A.J. (1971): On the distribution and metabolism of azaperone (R 1929) in the rat and pig. Arzneimittelforschung, 21, 982–984.

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