Reducing Viral Inhibition of Host Cellular Apoptosis Strengthens the Immunogenicity and Protective Efficacy of an Attenuated HSV-1 Strain
Author:
Publisher
Elsevier BV
Subject
Virology,Molecular Medicine,Immunology
Link
http://link.springer.com/content/pdf/10.1007/s12250-019-00156-7.pdf
Reference41 articles.
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3. Awasthi S, Lubinski JM, Eisenberg RJ, Cohen GH, Friedman HM (2008) An HSV-1 gD mutant virus as an entry-impaired live virus vaccine. Vaccine 26:1195–1203
4. Belshe RB, Leone PA, Bernstein DI, Wald A, Levin MJ, Stapleton JT, Gorfinkel I, Morrow RL, Ewell MG, Stokes-Riner A, Dubin G, Heineman TC, Schulte JM, Deal CD (2012) Efficacy results of a trial of a herpes simplex vaccine. N Engl J Med 366:34–43
5. Cartier A, Komai T, Masucci MG (2003) The Us3 protein kinase of herpes simplex virus 1 blocks apoptosis and induces phosporylation of the Bcl-2 family member Bad. Exp Cell Res 291:242–250
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