C-terminal domain of Chk1 regulates its subcellular location and kinase activity for DNA repair
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://link.springer.com/content/pdf/10.1007/s11434-011-4538-4.pdf
Reference28 articles.
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2. Zachos G, Rainey M D, Gillespie D A. Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects. EMBO J, 2003, 22: 713–723
3. Merry C, Fu K, Wang J, et al. Targeting the checkpoint kinase Chk1 in cancer therapy. Cell Cycle, 2010, 9: 279–283
4. Li X F, Ward T, Yao X B, et al. Chk1 prevents abnormal mitosis of S-phase HeLa cells containing DNA damage. Chinese Sci Bull, 2009, 54: 4205–4213
5. Ng C P, Lee H C, Ho C W, et al. Differential mode of regulation of the checkpoint kinases CHK1 and CHK2 by their regulatory domains. J Biol Chem, 2004, 279: 8808–8819
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1. Case report: A germline CHEK1 c.613 + 2T>C leads to a splicing error in a family with multiple cancer patients;Frontiers in Oncology;2024-04-15
2. Ral A, via activating the mitotic checkpoint, sensitizes cells lacking a functional Nf1 to apoptosis in the absence of protein kinase C;Oncotarget;2016-10-12
3. DNA damage, signaling and repair: Protecting genomic integrity and reducing the risk of human disease;Chinese Science Bulletin;2011-10
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