Inactivation of the positive LuxR-type oligomycin biosynthesis regulators OlmRI and OlmRII increases avermectin production in Streptomyces avermitilis

Author:

Yu Qing,Bai LinQuan,Zhou XiuFen,Deng ZiXin

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference39 articles.

1. Hopwood D A. Streptomyces in Nature and Medicine: The Antibiotic Makers. New York: Oxford University Press, 2007

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3. Bibb M J. Regulation of secondary metabolism in streptomycetes. Curr Opin Microbiol, 2005, 8: 208–215

4. Champness W C, Chater K F. Regulation and integration of antibiotic production and morphological differentiation in Streptomyces spp. In: Patrick Piggot C M, Youngman P, eds. Regulation of Bacterial Differentiation. Washington D.C.: American Society for Microbiology, 1994. 61–93

5. Fernandez-Moreno M A, Caballero J L, Hopwood D A, et al. The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces. Cell, 1991, 66: 769–780

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