Affiliation:
1. Institut Curie-Biologie, Centre Universitaire, Bat. 110, 91405 Orsay Cedex, France
Abstract
The carcinogenicity of several groups of carcinogens is evoked with particular reference to Dibenzo(c,g)carbazole derivatives. The activity of these derivatives is discussed with respect to their species and organ specificity. The enzymatic equipment is decisive as to whether the compounds formed can react with DNA or are simply detoxified and eliminated. All these carcinogens are complete carcinogens, i. e. they have the property of both initiation and promotion.
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
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