Pregabalin Controlled-Release Pharmacokinetics in Healthy Volunteers: Analysis of Four Multiple-Dose Randomized Clinical Pharmacology Studies

Author:

Chew Marci L.,Alvey Christine W.,Plotka Anna,Pitman Verne W.,Alebic-Kolbah Tanja,Scavone Joseph M.,Bockbrader Howard N.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),General Medicine

Reference25 articles.

1. Lyrica (pregabalin) [package insert]. New York: Pfizer Inc.; 2013. http://labeling.pfizer.com/ShowLabeling.aspx?id=561 . Accessed 18 July 2014.

2. Lyrica EU product information. Sandwich: Pfizer Limited; 2014. http://www.emea.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000546/WC500046602.pdf . Accessed 18 July 2014.

3. Corrigan BW, Pool WF, Posvar EL, et al. Metabolic disposition of pregabalin in healthy volunteers [abstract PI-68]. Clin Pharmacol Ther. 2001;69:P18.

4. Bockbrader HN, Radulovic LL, Posvar EL, et al. Clinical pharmacokinetics of pregabalin in healthy volunteers. J Clin Pharmacol. 2010;50:941–50.

5. Randinitis EJ, Posvar EL, Alvey CW, et al. Pharmacokinetics of pregabalin in subjects with various degrees of renal function. J Clin Pharmacol. 2003;43:277–83.

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