Phase I, First-in-Human, Single and Multiple Ascending Dose- and Food-Effect Studies to Assess the Safety, Tolerability and Pharmacokinetics of a Novel Anti-hepatitis B Virus Drug, Bentysrepinine (Y101), in Healthy Chinese Subjects-Reference-Cited by-同舟云学术

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Phase I, First-in-Human, Single and Multiple Ascending Dose- and Food-Effect Studies to Assess the Safety, Tolerability and Pharmacokinetics of a Novel Anti-hepatitis B Virus Drug, Bentysrepinine (Y101), in Healthy Chinese Subjects

Published:2020-04-10 Issue:6 Volume:40 Page:555-566
ISSN:1173-2563
Container-title:Clinical Drug Investigation
language:en
Short-container-title:Clin Drug Investig

Author:

Liu Xiaoxue^ORCID,Xue Ling,Zhang Hua,Xu Qingqing,Zhang Shichao,Ma Sheng,Ding Xiaoliang,Liu Linsheng,Dong Ji,Qian Lifang,Xia Wen,Jiang Kun,Huang Chenrong,Miao Liyan

Funder

the National Natural Science Foundation of China

the Ministry of Science and Technology of China

the Science and Technology Cooperation Major Project of Guizhou Province

National Key New Drug Creation and Manufacturing Program, Ministry of Science and Technology

Aosaikang Clinical Pharmacy Foundation

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s40261-020-00909-3.pdf

Reference25 articles.

1. Seto WK, Lo YR, Pawlotsky JM, Yuen MF. Chronic hepatitis B virus infection. Lancet. 2018;392:2313–24.

2. Ferreira MS, Borges AS. Advances in the treatment of hepatitis. Rev Soc Bras Med Trop. 2007;40:451–62.

3. Liang TJ. Hepatites B: the virus and disease. Hepatology. 2009;49:S13–21.

4. Ferreira CT, Silveira TR. Viral hepatitis prevention by immunization. J Pediatr. 2006;82:S55–66.

5. Ly KN, Xing J, Klevens RM, Jiles RB, Holmberg SD. Causes of death and characteristics of decedents with viral hepatitis. Clin Infect Dis. 2010;58:40–9.

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