A case of rapid avacopan-induced liver injury in pediatric granulomatosis with polyangiitis
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Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s00467-024-06376-8.pdf
Reference6 articles.
1. Jayne DR, Merkel PA, Schall TJ, Bekker P. ADVOCATE Study Group (2021) Avacopan for the treatment of ANCA-associated vasculitis. N Engl J Med 384:599–609
2. Zotta F, Diomedi-Camassei F, Gargiulo A, Cappoli A, Emma F, Vivarelli M (2023) Successful treatment with avacopan (CCX168) in a pediatric patient with C3 glomerulonephritis. Pediatr Nephrol 38:4197–4201
3. Kojima K, Fukui S, Tanigawa M, Sumiyoshi R, Koga T, Shimakura A, Okano S, Kawakami A (2024) Severe prolonged liver abnormality with jaundice during treatment for granulomatosis with polyangiitis with rituximab and avacopan. Rheumatology (Oxford) 63:e101–e103
4. Ennis D, Yeung RS, Pagnoux C (2020) Long-term use and remission of granulomatosis with polyangiitis with the oral C5a receptor inhibitor avacopan. BMJ Case Rep 13:e236236
5. Bekker P, Dairaghi D, Seitz L, Leleti M, Wang Y, Ertl L, Baumgart T, Shugarts S, Lohr L, Dang T, Miao S, Zeng Y, Fan P, Zhang P, Johnson D, Powers J, Jaen J, Charo I, Schall TJ (2016) Characterization of pharmacologic and pharmacokinetic properties of CCX168, a potent and selective orally administered complement 5a receptor inhibitor, based on preclinical evaluation and randomized phase 1 clinical study. PLoS ONE 11:e0164646
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