Structural Requirements of Some 2-(1-Propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide Derivatives as Poly (ADP-Ribose) Polymerase (PARP) for the Treatment of Cancer: QSAR Approach-Reference-Cited by-同舟云学术

Structural Requirements of Some 2-(1-Propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide Derivatives as Poly (ADP-Ribose) Polymerase (PARP) for the Treatment of Cancer: QSAR Approach

Published:2015-07-24 Issue:1 Volume:8 Page:11-22
ISSN:1913-2751
Container-title:Interdisciplinary Sciences: Computational Life Sciences
language:en
Short-container-title:Interdiscip Sci Comput Life Sci

Author:

Sharma Mukesh C.

Publisher

Springer Science and Business Media LLC

Subject

Health Informatics,Computer Science Applications,General Biochemistry, Genetics and Molecular Biology

Link

http://link.springer.com/content/pdf/10.1007/s12539-015-0015-0.pdf

Reference31 articles.

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3. Virág L (2005) Structure and function of poly (ADP-ribose) polymerase-1: role in oxidative stress-related pathologies. Curr Vasc Pharmacol 3:209–214

4. Rossi MN, Carbone M, Mostocotto C, Mancone C, Tripodi M, Maione R, Amati P (2009) Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity. J Biol Chem 284:31616–31624

5. Du X, Matsumura T, Edelstein D, Rossetti L, Zsengellér Z, Szabó C, Brownlee M (2003) Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. J Clin Invest 112:1049–1057

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