Can Pretreatment MRI and Planning CT Radiomics Improve Prediction of Complete Pathological Response in Locally Advanced Rectal Cancer Following Neoadjuvant Treatment?

Author:

Ramireddy Jeba Karunya,Sathya A.,Sasidharan Balu Krishna,Varghese Amal Joseph,Sathyamurthy Arvind,John Neenu Oliver,Chandramohan Anuradha,Singh Ashish,Joel Anjana,Mittal Rohin,Masih Dipti,Varghese Kripa,Rebekah Grace,Ram Thomas Samuel,Thomas Hannah Mary T.

Funder

Christian Medical College, Vellore

Publisher

Springer Science and Business Media LLC

Reference54 articles.

1. Feeney G, Sehgal R, Sheehan M, Hogan A, Regan M, Joyce M, et al. Neoadjuvant radiotherapy for rectal cancer management. World J Gastroenterol. 2019;25:4850–69. https://doi.org/10.3748/wjg.v25.i33.4850.

2. Hoendervangers S, Burbach JPM, Lacle MM, Koopman M, van Grevenstein WMU, Intven MPW, et al. Pathological complete response following different neoadjuvant treatment strategies for locally advanced rectal cancer: a systematic review and meta-analysis. Ann Surg Oncol. 2020;27:4319–36. https://doi.org/10.1245/s10434-020-08615-2.

3. Shin JK, Huh JW, Lee WY, Yun SH, Kim HC, Cho YB, et al. Clinical prediction model of pathological response following neoadjuvant chemoradiotherapy for rectal cancer. Sci Rep. 2022;12:7145. https://doi.org/10.1038/s41598-022-10974-7.

4. Conroy T, Bosset J-F, Etienne P-L, Rio E, François É, Mesgouez-Nebout N, et al. Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol. 2021;22:702–15. https://doi.org/10.1016/S1470-2045(21)00079-6.

5. Bahadoer RR, Dijkstra EA, van Etten B, Marijnen CAM, Putter H, Kranenbarg EM-K, et al. Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial. Lancet Oncol. 2021;22:29–42. https://doi.org/10.1016/S1470-2045(20)30555-6.

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