Adequately defining tumor cell proportion in tissue samples for molecular testing improves interobserver reproducibility of its assessment
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology,General Medicine,Pathology and Forensic Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00428-016-2042-6.pdf
Reference9 articles.
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2. Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, Harris PL, Haserlat SM, Supko JG, Haluska FG, Louis DN, Christiani DC, Settleman J, Haber DA (2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefinitib. N Engl J Med 350:2129–2139
3. Pao W, Miller V, Zakowski M, Doherty J, Politi K, Sarkaria I, Singh B, Heelan R, Rusch V, Fulton L, Mardis E, Kupfer D, Wilson R, Kris M, Varmus H (2004) EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 101:13306–13331
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5. Viray H, Li K, Long TA, Vasalos P, Bridge JA, Jennings LJ, Halling KC, Hameed M, Rimm DL (2013) A prospective, multi-institutional diagnostic trail to determine pathologist accuracy in estimation of percentage of malignant cells. Arch Pathol Lab Med 137:1545–1549. doi: 10.5858/arpa.2012-0561-CP
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