Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in advanced gastric carcinomas

Author:

Wang Jaw-Yuan,Huang Tsung-Jen,Chen Fang-Ming,Hsieh Ming-Chia,Lin Shiu-Ru,Hou Ming-Feng,Hsieh Jan-Sing

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology,General Medicine,Pathology and Forensic Medicine

Reference42 articles.

1. Bose K, Crane A, Hibshoosh H, Manaukhani M, Sandweis L, Parsons R (2002) Reduced expression of PTEN correlates with breast cancer progression. Hum Pathol 33:405–409

2. Bostrom J, Cobbers JM, Wolter M, Tabatabai G, Weber RG, Lichter P, Collins VP, Reifenberger G (1998) Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q. Cancer Res 58:29–33

3. Cairns P, Okami K, Halachmi S, Halachmi N, Esteller M, Herman JG, Jen J, Isaacs WB, Bova GS, Sidransky D (1997) Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. Cancer Res 57:4997–5000

4. Chang JG, Chen YJ, Perng LI, Wang NM, Kao MC, Yang TY, Chang CP, Tsai CH (1999) Mutation analysis of the PTEN/MMAC1 gene in cancers of the digestive tract. Eur J Cancer 35:647-651

5. Dahia PL (2000) PTEN, a unique tumor suppressor gene. Endocr Relat Cancer 7:115–129

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