Development of bambuterol; a long acting, orally active beta-agonist prodrug

Author:

Svensson Leif-Ake

Publisher

Springer Vienna

Reference30 articles.

1. Bauer CA, Svenson L-Å (1992) Bambuterol (Bambec®): A new long-acting oral bronchodilator. Drugs of Today 28: 547–557

2. Kristoffersson J, Svensson L-Å, Tegnér K (1974) Drug latentiation of terbutaline. In vitro serum esterase catalyzed hydrolysis of a series of acylsubstituded mono-and diesters of terbutaline. Acta Pharm Suec 11: 427–438

3. Hörnblad Y, Ripe E, Magnusson PO, Tegnér K (1976) The metabolic and clinical activity of terbutaline and its ester prodrug ibuterol. Eur J Clin Pharmacol 10: 9–18

4. Ryrfeldt Å, Nilsson E (1978) Uptake and biotransformation of ibuterol and terbutaline in isolated perfused rat and guinea pig lungs. Biochem Pharmacol 27: 301–305

5. Svensson L-Å (1987) Development of β2-adrenoceptor agonist bronchodilator prodrugs. In: Hollinger MA (ed) Current topics in pulmonary pharmacology and toxicology, Vol. 3. Elsevier, New York, 1–26

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