Population pharmacodynamic modelling of lorazepam- and midazolam-induced sedation upon long-term continuous infusion in critically ill patients-Reference-Cited by-同舟云学术

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Population pharmacodynamic modelling of lorazepam- and midazolam-induced sedation upon long-term continuous infusion in critically ill patients

Published:2006-01-20 Issue:3 Volume:62 Page:185-194
ISSN:0031-6970
Container-title:European Journal of Clinical Pharmacology
language:en
Short-container-title:Eur J Clin Pharmacol

Author:

Swart Eleonora L.,Zuideveld Klaas P.,de Jongh Joost,Danhof Meindert,Thijs Lambertus G.,Strack van Schijndel Robert M. J.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00228-005-0085-8.pdf

Reference23 articles.

1. Swart EL, Strack van Schijndel RJM, van Loenen AC, Thijs LG (1999) Continuous infusion of lorazepam versus midazolam in patients in the intensive care unit: sedation with lorazepam is easier to manage and is more cost-effective. Crit Care Med 27:1461–1465

2. Swart EL, Zuideveld KP, de Jongh J, Danhof M, Thijs LG, Strack van Schijndel RJM (2004) Comparative population pharmacokinetics of lorazepam and midazolam upon long-term continuous infusion in critically ill patients. Br J Clin Pharmacol 57:135–145

3. Mandema JW, Tuk B, van Steveninck AL, Breimer DD, Cohen AF, Danhof M (1992) Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite α-hydroxymidazolam in healthy volunteers. Clin Pharmacol Ther 51:715–728

4. Barr J, Zomorodi K, Bertaccini EJ, Shafer SL, Geller E (2001) A double-blind, randomized comparison of IV lorazepam versus midazolam for sedation of ICU patients via a pharmacologic model. Anesthesiology 95:286–298

5. Knaus WA, Draper EA, Wagner DP, Zimmerman JE (1985) APACHE II: a severity of disease classification system. Crit Care Med 13:818–829

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