Effects of growth hormone deficiency and rhGH replacement therapy on the 6?-hydroxycortisol/free cortisol ratio, a marker of CYP3A activity, in growth hormone-deficient children

Author:

Sinu�s Blanca,Mayayo Esteban,Fanlo Ana,JR Esteban Mayayo,Bernal Mar�a L.,Bocos Pilar,Bello Elena,Labarta Jose I.,Ferr�ndez-Long�s Angel

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference48 articles.

1. Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP (1994) Interindividual variations in the human liver cytochrome P450 enzyme involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 270:414?423

2. de Wildt SN, Kearns GL, Leeder JS, van den Anker JN (1999) Cytochrome P4503A: ontogeny and drug disposition. Clin Pharmacokinet 37:485?505

3. Gallagher EP, Wienkers LC, Stapleton PL, Kunze K, Eaton DL (1994) Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1. Cancer Res 54:101?108

4. Guengerich FP (1991) Oxidation of toxic and carcinogenic chemicals by human cytochrome P450 enzymes. Chem Res Toxicol 4:391?407

5. Watkins PB, Turgeon DK, Saenger P, Lown KS, Kolars JC, Hamilton T, Fishman K, Guzelian PS, Voorhees JJ (1992) Comparison of urinary 6-beta-cortisol and the erythromycin breath test as measures of hepatic P450 IIIA (CYP3A) activity. Clin Pharmacol Ther 52:265?273

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