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Subtherapeutic valproic acid plasma concentrations under concomitant dipyrone therapy in an epilepsy patient—a case report

  • Published:2018-01-23 Issue:5 Volume:74 Page:675-677
  • ISSN:0031-6970
  • Container-title:European Journal of Clinical Pharmacology
  • language:en
  • Short-container-title:Eur J Clin Pharmacol

Author:

Morath Benedict,Green K.,Zaradzki M.,Heid J.,Karck M.,Hoppe-Tichy T.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference13 articles.

1. Loscher W (2002) Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy. CNS drugs 16(10):669–694. https://doi.org/10.2165/00023210-200216100-00003

2. Mahli GS, Adams D, Cahill CM, Dodd S, Berk M (2009) The management of individuals with bipolar disorder: a review of the evidence and its integration into clinical practice. Drugs 69(15):2063–2101. https://doi.org/10.2165/11318850-000000000-00000

3. Fleming J, Chetty M (2005) Psychotropic drug interactions with valproate. Clin Neuropharmacol 28(2):96–101. https://doi.org/10.1097/01.wnf.0000154221.37887.73

4. Tan L, Yu JT, Sun YP, Ou JR, Song JH, Yu Y (2010) The influence of cytochrome oxidase CYP2A6, CYP2B6, and CYP2C9 polymorphisms on the plasma concentrations of valproic acid in epileptic patients. Clin Neurol Neurosurg 112(4):320–323. https://doi.org/10.1016/j.clineuro.2010.01.002

5. Hiemke C, Bergemann N, Clement HW, Conca A, Deckert J, Domschke K, Eckermann G, Egberts K, Gerlach M, Greiner C, Grunder G, Haen E, Havemann-Reinecke U, Hefner G, Helmer R, Janssen G, Jaquenoud E, Laux G, Messer T, Mossner R, Muller MJ, Paulzen M, Pfuhlmann B, Riederer P, Saria A, Schoppek B, Schoretsanitis G, Schwarz M, Gracia MS, Stegmann B, Steimer W, Stingl JC, Uhr M, Ulrich S, Unterecker S, Waschgler R, Zernig G, Zurek G, Baumann P (2017) Consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology: update 2017. Pharmacopsychiatry. https://doi.org/10.1055/s-0043-116492

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Gephyrin and CYP2C9 Genetic Polymorphisms in Patients with Pharmacoresistant Epilepsy;Pharmacogenomics and Personalized Medicine;2021-09

2. Dipyrone/valproic acid interaction;Reactions Weekly;2018-05
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