Bearing variant alleles at uridine glucuronosyltransferase polymorphisms UGT2B7 -161C > T (rs7668258) or UGT1A4*3 c.142 T > G (rs2011425) has no relevant consequences for lamotrigine troughs in adults with epilepsy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00228-023-03526-z.pdf
Reference45 articles.
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3. Patsalos PN (2016) Antiepileptic drug interactions. a clinical guide. 3rd ed. London, UK, Springer, pp. 55–59
4. Methaneethorn J, Leelakanok N (2020) Sources of lamotrigine pharmacokinetic variability: a systematic review of population pharmacokinetic analyses. Eur J Epilepsy 82:133–147
5. Reimers A, Andsnes Berg J, Burns ML, Brodtkorb E, Johannessen SI, Johannessen Landmark C (2018) Reference ranges for antiepileptic drugs revisited: a practical approach to establish national guidelines. Drug Design Dev Ther 12:271–280
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