Pharmacokinetics of free and total mycophenolic acid in adult lupus nephritis patients—implications for therapeutic drug monitoring

Author:

Łuszczyńska PaulinaORCID,Pawiński Tomasz,Kunicki Paweł K.,Durlik Magdalena,Augustyniak-Bartosik Hanna,Hurkacz Magdalena

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference26 articles.

1. Bertsias GK, Tektonidou M, Amoura Z, Aringer M, Bajema I, Berden JH, Boletis J, Cervera R, Dorner T, Doria A, Ferrario F, Floege J, Houssiau FA, Ioannidis JP, Isenberg DA, Kallenberg CG, Lightstone L, Marks SD, Martini A, Moroni G, Neumann I, Praga M, Schneider M, Starra A, Tesar V, Vasconcelos C, van Vollenhoven RF, Zakharova H, Haubitz M, Gordon C, Jayne D, Boumpas DT (2012) Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis. Ann Rheum Dis 71:1771–1782. https://doi.org/10.1136/annrheumdis-2012-201940

2. Abd Rahman AN, Tett SE, Abdul Gafor HA, McWhinney BC, Staatz CE (2015) Exposure-effect relationship of mycophenolic acid and prednisolone in adult patients with lupus nephritis. Br J Clin Pharmacol 80:1064–1075. https://doi.org/10.1111/bcp.12678

3. Shaw LM, Holt DW, Oellerich M, Meiser B, Van Gelder T (2001) Current issues in therapeutic drug monitoring of mycophenolic acid: report of a roundtable discussion. Ther Drug Monit 23:305–315

4. Le Meur Y, Buchler M, Thierry A, Caillard S, Villemain F, Lavaud S, Etienne I, Westeel PF, Hurault de Ligny B, Rostaing L, Thervet E, Szelag JC, Rerolle JP, Rousseau A, Touchard G, Marquet P (2007) Individualized mycophenolate mofetil dosing based on drug exposure significantly improves patient outcomes after renal transplantation. Am J Transplant 7:2496–2503. https://doi.org/10.1111/j.1600-6143.2007.01983.x

5. Łuszczyńska P, Pawiński T (2015) Therapeutic drug monitoring of mycophenolic acid in lupus nephritis: a review of current literature. Ther Drug Monit 37:711–717. https://doi.org/10.1097/FTD.0000000000000223

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