The safety and efficacy of dabrafenib and trametinib in patients with glioma: A systematic review and meta-analysis
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Springer Science and Business Media LLC
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https://link.springer.com/content/pdf/10.1007/s00228-024-03635-3.pdf
Reference12 articles.
1. Bouffet E et al (2023) Efficacy and safety of trametinib monotherapy or in combination with dabrafenib in pediatric BRAF V600-mutant low-grade glioma. J Clin Oncol 41(3):664–674
2. Hargrave DR, Investigators involved in the high-grade glioma cohort et al (2023) Phase II trial of dabrafenib plus trametinib in relapsed/refractory BRAF V600-mutant pediatric high-grade glioma. J Clin Oncol 41(33):5174–5183. https://doi.org/10.1200/JCO.23.00558. Epub 2023 Aug 29
3. Wen PY et al (2022) Dabrafenib plus trametinib in patients with BRAF(V600E)-mutant low-grade and high-grade glioma (ROAR): a multicentre, open-label, single-arm, phase 2, basket trial. Lancet Oncol 23(1):53–64
4. Johanns TM et al (2018) Rapid clinical and radiographic response with combined dabrafenib and trametinib in adults with BRAF-mutated high-grade glioma. J Natl Compr Canc Netw 16(1):4–10
5. Geoerger B et al (2020) Dabrafenib + trametinib combination therapy in pediatric patients with BRAF V600-mutant low-grade glioma: safety and efficacy results. J Clin Oncol 38(15):10506–10506
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