Combining Melphalan Percutaneous Hepatic Perfusion with Ipilimumab Plus Nivolumab in Advanced Uveal Melanoma: First Safety and Efficacy Data from the Phase Ib Part of the Chopin Trial
Author:
Funder
Bristol-Myers Squibb
Delcath Systems Inc.
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine,Radiology, Nuclear Medicine and imaging
Link
https://link.springer.com/content/pdf/10.1007/s00270-022-03338-1.pdf
Reference38 articles.
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4. Algazi AP, Tsai KK, Shoushtari AN, Munhoz RR, Eroglu Z, Piulats JM, et al. Clinical outcomes in metastatic uveal melanoma treated with PD-1 and PD-L1 antibodies. Cancer. 2016;122(21):3344–53.
5. Kelderman S, van der Kooij MK, van den Eertwegh AJM, Soetekouw PMMB, Jansen RLH, van den Brom RRH, Hospers GAP, Haanen JBAG, Kapiteijn E, Blank CU. Ipilimumab in pretreated metastastic uveal melanoma patients. Results of the dutch working group on immunotherapy of oncology (WIN-O). Acta Oncologica. 2013;52(8):1786–8. https://doi.org/10.3109/0284186X.2013.786839.
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1. ASO Author Reflections: Optimizing Line of Therapy with the Melphalan/Hepatic Delivery System for Metastatic Uveal Melanoma;Annals of Surgical Oncology;2024-08-28
2. A phase Ib randomized multicenter trial of isolated hepatic perfusion in combination with ipilimumab and nivolumab for uveal melanoma metastases (SCANDIUM II trial);ESMO Open;2024-07
3. The Current State of Systemic Therapy of Metastatic Uveal Melanoma;American Journal of Clinical Dermatology;2024-06-22
4. Efficacy and Safety of the Melphalan/Hepatic Delivery System in Patients with Unresectable Metastatic Uveal Melanoma: Results from an Open-Label, Single-Arm, Multicenter Phase 3 Study;Annals of Surgical Oncology;2024-05-04
5. ASO Author Reflections: Percutaneous Hepatic Perfusion: Past, Present, and Future;Annals of Surgical Oncology;2024-04-29
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