Cinnamaldehyde targets TLR-4 and inflammatory mediators in acetic-acid induced ulcerative colitis model

Author:

Momtaz SaeidehORCID,Navabakhsh MaryamORCID,Bakouee NeginORCID,Dehnamaki MustafaORCID,Rahimifard MahbanORCID,Baeeri MaryamORCID,Abdollahi AlirezaORCID,Abdollahi MohammadORCID,Farzaei Mohamad Hosein,Abdolghaffari Amir HosseinORCID

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Plant Science,Genetics,Molecular Biology,Animal Science and Zoology,Biochemistry,Ecology, Evolution, Behavior and Systematics

Reference58 articles.

1. Agliata I, Fernandez-Jimenez N, Goldsmith C, Marie JC, Bilbao JR, Hernandez-Vargas HD (2019) The DNA Methylome of inflammatory bowel disease (IBD) reflects intrinsic and extrinsic factors in intestinal epithelial cells. BioRxiv. https://doi.org/10.1101/565200

2. Algieri F, Zorrilla P, Rodriguez-Nogales A, Garrido-Mesa N, Bañuelos Ó, González-Tejero MR, Casares-Porcel M, Molero-Mesa J, Zarzuelo A, Utrilla MP (2013) Intestinal anti-inflammatory activity of hydroalcoholic extracts of Phlomis purpurea L. and Phlomis lychnitis L. in the trinitrobenzenesulphonic acid model of rat colitis. J Ethnopharmacol 146(3):750–759. https://doi.org/10.1016/j.jep.2013.01.041

3. Amiri M, Navabi J, Shokoohinia Y, Heydarpour F, Bahrami G, Behbood L, Derakhshandeh P, Momtaz S, Farzaei MH (2019) Efficacy and safety of a standardized extract from Achillea wilhelmsii C. Koch in patients with ulcerative colitis: a randomized double blind placebo-controlled clinical trial. Complement Ther Med 45:262–268. https://doi.org/10.1016/j.ctim.2019.05.001

4. Chao LK, Hua KF, Hsu HY, Cheng SS, Lin IF, Chen CJ, Chen ST, Chang ST (2008) Cinnamaldehyde inhibits pro-inflammatory cytokines secretion from monocytes/macrophages through suppression of intracellular signaling. Food Chem Toxicol 46(1):220–231. https://doi.org/10.1016/j.fct.2007.07.016

5. Chiang YF, Chen HY, Huang KC, Lin PH, Hsia SM (2019) Dietary antioxidant trans-cinnamaldehyde reduced visfatin-induced breast cancer progression: in vivo and in vitro study. Antioxidants 8(12):625. https://doi.org/10.3390/antiox8120625

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