In silico design and in vitro expression of novel multiepitope DNA constructs based on HIV-1 proteins and Hsp70 T-cell epitopes
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Biotechnology,Bioengineering,Applied Microbiology and Biotechnology
Link
https://link.springer.com/content/pdf/10.1007/s10529-021-03143-9.pdf
Reference45 articles.
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2. Andrade RM et al (2007) Interleukin-10-secreting CD4 cells from aged patients with AIDS decrease in-vitro HIV replication and tumour necrosis factor α production. AIDS 21:1763–1770. https://doi.org/10.1097/QAD.0b013e3282ca83fa
3. Bento CA et al (2009) IL-10-secreting T cells from HIV-infected pregnant women downregulate HIV-1 replication: effect enhanced by antiretroviral treatment. AIDS 23:9–18. https://doi.org/10.1097/QAD.0b013e328317461e
4. Brockman MA et al (2009) IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells. Blood 114:346–356. https://doi.org/10.1182/blood-2008-12-191296PMCID:PMC2714209
5. Cheng L et al (2017) Type I interferons suppress viral replication but contribute to T cell depletion and dysfunction during chronic HIV-1 infection. JCI Insight 2(12):e94366. https://doi.org/10.1172/jci.insight.94366
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