Enhanced production of l-methionine in engineered Escherichia coli with efficient supply of one carbon unit

Author:

Tang Xiao-Ling,Du Xu-Yuan,Chen Lu-Jia,Liu Zhi-QiangORCID,Zheng Yu-Guo

Funder

National Basic Research Program of China

Publisher

Springer Science and Business Media LLC

Subject

General Medicine,Biotechnology,Bioengineering,Applied Microbiology and Biotechnology

Reference19 articles.

1. Chen XL, Gao C, Guo L, Hu GP, Luo QL, Liu J, Nielsen J, Chen J, Liu LM (2018) DCEO biotechnology: tools to design, construct, evaluate, and optimize the metabolic pathway for biosynthesis of chemicals. Chem Rev 118(1):4–72

2. Figge RM (2007) Methionine biosynthesis in Escherichia coli and Corynebacterium glutamicum. In: Wendisch VF (ed) Amino acid biosynthesis pathways, regulation and metabolic engineering. Springer, Berlin

3. Figge R, Dumon Seignovert L, Vasseur P, Dischert W (2016) Method and microorganism for methionine production by fermentation with improved methionine efflux. European Patent WO 2016034536 A1.

4. Hondorp ER, Matthews RG (2009) Oxidation of cysteine 645 of cobalamin-independent methionine synthase causes a methionine limitation in Escherichia coli. J Bacteriol 191(10):3407–3410

5. Huang JF, Liu ZQ, Jin LQ, Tang XL, Shen ZY, Yin HH, Zheng YG (2017) Metabolic engineering of Escherichia coli for microbial production of L-methionine. Biotechnol Bioeng 114(4):843–851

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